解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::A silicone-based prepolymer was used as the major component for the fabrication of novel ocular devices. Gentamicin sulphate was used as a probe drug, due to its high aqueous solubility and widespread application. Mechanical properties of films containing the drug before and after gamma sterilization and exposure to h...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(90)90035-o
更新日期:1990-11-01 00:00:00
abstract::Hydroxyapatite (HA) and beta-tricalcium phosphate (TCP) were studied by computer graphics with a personal computer. Crystal models of fluoridated hydroxyapatite and fluorapatite, in which F- ions are substituted into some or all OH- positions, were also drawn. Data on the structural coordinates of the hydroxyapatite a...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(90)90081-z
更新日期:1990-10-01 00:00:00
abstract::A homogeneous glycidyl acrylate polymer (GAP) has been grafted on to polytetrafluoroethylene (PTFE) and polyethylene (PE) using a modified plasma glow discharge technique with glycidyl acrylate. The polymeric layer appears to be extremely stable to acidic media and to common organic solvents. The modified surface can ...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(90)90083-3
更新日期:1990-10-01 00:00:00
abstract::In vitro solubility tests of hydroxyapatite, tetracalcium phosphate or tricalcium phosphate particles were performed in lactate, citrate, Gomoris or Michaelis buffer with pH 6.2 or 7.2 and in aqua destillata. The results showed that in general the solubility decreased in the order tetracalcium phosphate greater than t...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(90)90067-z
更新日期:1990-09-01 00:00:00
abstract::The fracture toughness of three polymethacrylate contact lens hydrogel materials was measured using the method of Generalized Fracture Mechanics. One hydrogel (SNOFLEX S68) had a significantly higher fracture energy per unit area (Jc) than the others, probably because it undergoes plastic deformation at high strains. ...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(90)90095-8
更新日期:1990-08-01 00:00:00
abstract::Thermostimulated current spectroscopy has been applied to the investigation of molecular mobility in human calcified tissue. A comparative study of extracts at various stages of demineralization is presented. The response of an organic-mineral complex interphase has been identified. ...
journal_title:Biomaterials
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract::Long-term (8 and 24 month) reactions of the (hypo) dermis of the guinea pig to solid and porous (50 vol%) acrylic implants and four human biopsies from porous subcutaneous acrylic implants were studied light microscopically. The solid implants were encapsulated by dense connective tissue. Mobility was evidenced by the...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(90)90105-y
更新日期:1990-07-01 00:00:00
abstract::Materials for orthopaedic implants can fail for several combined reasons: corrosion, fatigue and wear for metals, wear and creep for polymers, fracture for ceramics. Some typical cases are analysed and it is demonstrated that ion implantation improves metals and polymers used for joint prosthesis. Implantations of nit...
journal_title:Biomaterials
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract::In vitro experiments were conducted upon some common metallic biomaterials and carbons, both isolated or forming galvanic couples, in a cell specially designed for crevice corrosion studies. The alloys examined were AISI 316L stainless steel, Ti6AI4V and Co-Cr-Mo. The types of carbon were glassy carbon and carbon fibr...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(90)90110-c
更新日期:1990-07-01 00:00:00
abstract::The changes in protein adsorption onto aluminium surfaces coated with different thicknesses of oxide layers were examined. The oxide layers on aluminium substrates were derived by the anodizing technique. Protein adsorption studies were conducted using 125I-labelled albumin and the amount of albumin adsorbed was estim...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(90)90006-c
更新日期:1990-05-01 00:00:00
abstract::The non-collagenous proteins of mature cortical rabbit bone and 3 wk old bone specimens formed in titanium implant bone harvest chambers, were separated by means of fine pressure liquid chromatography. It was found that a sufficient amount of bone could be obtained from five bone harvest chambers in five rabbits durin...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(90)90158-m
更新日期:1990-04-01 00:00:00
abstract::Two new absorbable monofilament suture materials polydioxanone and Maxon are being employed increasingly in abdominal surgery because of increased strength retention and decreased tissue reactivity compared with previously available materials. As part of our investigation of the behaviour of suture materials, 3-0 sutu...
journal_title:Biomaterials
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Hydroxyapatite ceramics with zirconia dispersion from fine powders synthesized hydrothermally were post-sintered at 1000-1300 degrees C under 200 MPa of argon for 1 h without capsules, after normal sintering in air at 1200 degrees C for 3 h. Densification was most significant with post-sintering at 1200 degrees C. Fra...
journal_title:Biomaterials
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::To develop artificial materials for prolonged use in the vascular system, the complicated process of surface-induced thrombosis needs to be better understood. Steroidal hormones have a profound role in thrombosis and haemostasis, although adequate studies are not available to demonstrate their part in the thromboembol...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(89)90115-4
更新日期:1989-11-01 00:00:00
abstract::The in vitro adhesion and spreading of human endothelial cells (HEC) on hydrophobic poly(ethylene terephthalate) (PETP) and moderately wettable tissue culture poly(ethylene terephthalate) (TCPETP) were studied with light microscopy and electron microscopy. Numbers of HEC adhering on TCPETP were always higher than thos...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(89)90058-6
更新日期:1989-10-01 00:00:00
abstract::The elasticity, mechanical strength and permeability of a new biomaterial made of elastin and fibrin were investigated. It was shown that gamma-irradiation to sterilize the product, and sulphur derivatives (Merceptyl, thiourea, cystein) working as reticulating agents modified these properties. Depending on whether or ...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(89)90084-7
更新日期:1989-09-01 00:00:00
abstract::A new system of single piece electrodes was applied to in vivo and in vitro measurements of anodic polarization of several alloys used in orthopaedic implants. The tested surface was scrutinized with a stereomicroscope after each experiment. This confirmed pit formation and excluded the possibility of other sudden inc...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(89)90134-8
更新日期:1989-08-01 00:00:00
abstract::Many joint diseases are associated with the deposition of crystals in articular cartilage. Three main types are commonly found: calcium pyrophosphate, calcium hydroxyapatite and monosodium urate. The effects of these articular crystals on the frictional properties and the surface condition of the articular cartilage w...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(89)90074-4
更新日期:1989-07-01 00:00:00
abstract::Forty squares of tissue, 40 mm X 40 mm, were harvested from bovine pericardium fixed in glutaraldehyde free of tension. Two parallel dumb-bell specimens were excised from each square. In 20 pairs of adjacent samples, two 1 mm cuts were introduced into one of the samples at the centre of the dumb-bell. The other 20 pai...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(89)90098-7
更新日期:1989-05-01 00:00:00
abstract::Semiconduction activation energies of adenine, guanine, thymine and uracil complexes with acridine orange dye at various dye concentrations were measured in both Ohmic and space charge limited (SCL) current regimes. The behaviour of the complexes is non-extrinsic at high dye concentrations but extrinsic at low dye con...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(89)90025-2
更新日期:1989-04-01 00:00:00
abstract::The reaction of calcium ions and organic phosphate ester monomer at varying pHs was examined. Above pH 10, poorly crystallized hydroxyapatite was formed, which had lower crystallinity than that synthesized with inorganic phosphate as a source of P under the same conditions. On the other hand, the results of X-ray diff...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(89)90045-8
更新日期:1989-03-01 00:00:00
abstract::The bulk, surface and blood-contacting properties of a series of polyether polyurethanes, modified with three different polydimethylsiloxane (PDMS) macroglycol segments, were evaluated. The PDMS oligomers were terminated with hydroxy-tipped end groups of varying polarity. The effect of substituting the polytetramethyl...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(89)90005-7
更新日期:1989-01-01 00:00:00
abstract::The Raman laser and infrared spectra of doped bio-active glasses of the 45S5 type are presented and discussed. The spectroscopic results show that the doping agents cause the destruction of the basic glass structure and the consequent formation of SiO4(4-) units in the glass network. When the doped glasses have been i...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(88)90050-6
更新日期:1988-11-01 00:00:00
abstract::We have prepared a fraction of commercial fetal calf serum whose major component comprises proteins of apparent molecular mass 65-80 kDa. These preparations elicit cell spreading responses in serum-free medium at concentrations similar to those reported for human vitronectin. In addition, we have identified (by a prot...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(88)90049-x
更新日期:1988-11-01 00:00:00
abstract::Long-term elution of fluoride ions has been studied for one silicate and six glass-ionomer cements over a period of some two and-a-half years. Because equilibrium was not reached, classical diffusion theory could not be applied to the process. It was postulated that two elution processes were taking place, one short-t...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(88)90012-9
更新日期:1988-09-01 00:00:00
abstract::Polystyrene and phenylated polyacrolein microspheres of different diameters, as well as modified cellulose microspheres with different surface charges, were prepared in order to study the size and surface charge effect on their phagocytosis by mouse peritoneal macrophages. It was found that the maximal phagocytosis of...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(88)90033-6
更新日期:1988-07-01 00:00:00
abstract::Palladium additions to a dispersed phase high-copper amalgam have been shown recently to suppress markedly the eta' (Cu6Sn5) concentration and decrease creep. A detailed study of the dental and 24 h creep for Pd containing high-copper amalgams and six commercial controls as a function of applied temperature and stress...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(88)90086-5
更新日期:1988-05-01 00:00:00
abstract::The object of this study was to develop a small experimental animal model for a systematic study of the interfacial phenomena between percutaneous implants and skin. Plasma-sprayed and dense hydroxyapatite test implants were inserted into the tibia and dorsum of guinea pigs and into the tibia and on the cranium of rab...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(88)90096-8
更新日期:1988-05-01 00:00:00
abstract::The adhesion and growth of cells on silicon dioxide substrata are analysed. The adhesion of human red blood cells to silicon dioxide layers of different depth and doping compares well with that to glass. Rat pheochromocytoma cells also grow on the same substrata. The adhesion of these two biological systems is charact...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(88)90079-8
更新日期:1988-01-01 00:00:00
abstract::Linear alkyl chains containing 2, 10 and 18 carbon atoms were grafted to 10% of the urethane nitrogens in a polyether-polyurethane. The polyurethane was synthesized from methylene bis(p-phenyl isocyanate), 1,4-butanediol, and polytetramethylene oxide of 1000 molecular weight in a molar ratio of 3/2/1. Fourier transfor...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(88)90067-1
更新日期:1988-01-01 00:00:00
abstract::There is a growing demand for the production of a DNA biosensor with applications in medicine, the food industry, agriculture, veterinary science and environmental science. In this paper we describe methods for the optical and electrochemical detection of DNA using the enzyme horseradish peroxidase (EC 1.11.1.7) and g...
journal_title:Biomaterials
pub_type: 杂志文章,评审
doi:10.1016/0142-9612(88)90072-5
更新日期:1988-01-01 00:00:00
abstract::This study addresses the problem of antibiotic resistance in adhesive, biomaterial-centred infections. It is suggested that this anionic, extracapsular, polysaccharide slime produced by bacteria protects them from antibiotics and sequesters critical ions from the surface of biomaterials. Biofilm-enclosed bacteria on t...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(87)90077-9
更新日期:1987-11-01 00:00:00
abstract::A surface with covalently bonded heparin was tested in an in vivo model. Heparinized and non-heparinized tubings were inserted in the pig aorta. They were left in place for up to 16 wk. After removal they were analysed for their capacity to take up and inhibit thrombin. A comparison was also made with tubings that had...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(87)90088-3
更新日期:1987-11-01 00:00:00
abstract::A general solution of the diffusion equation for gas in polymers is developed by a numerical method. This solution allows diffusion to be calculated in all cases, by gas desorption after an incomplete adsorption, which is not the case for analytical solutions. When the analytical solutions are valid, both types of sol...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(87)90004-4
更新日期:1987-09-01 00:00:00
abstract::Measurements were made of the extremes in temperature which occur at different sites in the oral cavity during fluid intake. The results indicate that temperatures noted at the tooth surface, within the mouth, during fluid intake were less than the temperatures of the fluid imbibed. Variations in temperature were note...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(87)90016-0
更新日期:1987-09-01 00:00:00
abstract::A range of poly(alkyl methacrylate)s in the range C5 to C13 with varying degrees of crosslinking, have been studied with respect to stress-strain behaviour. Where the extensions to break were sufficiently high, stress-strain properties conformed well to the statistical theory of rubber elasticity, the Mooney/Rivlin C2...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(87)90011-1
更新日期:1987-09-01 00:00:00
abstract::In vivo and in vitro degradation of high molecular weight poly(L-lactide) used for internal bone fixation has been investigated. Within 3 months as-polymerized, microporous PLLA (Mv = 6.8-9.5 X 10(5] exhibited a massive strength-loss (sigma b = 68-75 MPa to sigma b = 4 MPa) and decrease of Mv (90-95%). At week 39, the...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(87)90121-9
更新日期:1987-07-01 00:00:00
abstract::The in vivo performance of 250 retrieved internal fixation plates was evaluated. The corrosion characteristics and metallurgical properties of each implant were assessed and correlated with respective clinical performance. Screw-plate interface corrosion and screw surface corrosion were graded; Rockwell hardness, grai...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(87)90060-3
更新日期:1987-05-01 00:00:00
abstract::The effect of surface characteristics on the interaction of sterically stabilized polystyrene particles with mouse peritoneal macrophages was studied using a range of poloxamers and poloxamine as coating agents. The coated particles were characterized in terms of thickness of coating layer, surface charge and critical...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(87)90099-8
更新日期:1987-03-01 00:00:00
abstract::Poly(L-lactide) (PLLA) with an extremely high molecular weight (Mv up to 1 X 10(6)) was synthesized at a low catalyst concentration (0.015 wt%) and temperatures between 100-110 degrees C. Besides good mechanical properties the as-polymerized PLLA exhibited a microporous structure. Plates and screws of this material we...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(87)90034-2
更新日期:1987-01-01 00:00:00